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KMID : 0366219900250020605
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Korean Journal of Hematology
1990 Volume.25 No. 2 p.605 ~ p.611
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A Case of Histiocytic Hyperplasia With Hemophagocytosis Benign Hemophagoytic Syndrome
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이준호/Jun Ho Lee
양하영/이혜란/최찬옥/박장필/진태선/현재란/박영희/Ha Young Yang/Hye Ran Lee/Chan Ok Choi/Jang Pil Park/Tae Sun Jin/Jae Ran Hyun/Young Hee Park
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Abstract
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Proliferation of histiocytes and hemophagocytosis could be occur in some bacterial or
viral infections, so it is called by benign hemophagocytic syndrome(BHS) due to it's
non-malignant histologic features. But in some cases, BHS is rapidly fatal without
evidence of infections and simulate HMR clinically, so make it difficult to manage and
treatment. In BHS, we think it is mandatory to reexamine the bone marrow study and
do hybridization technique for the viral infections in seronegative group to exclude the
possibility of secondary phenomenon. We experienced a fatal case of massive systemic
proliferation of mature histiocytes with hemophagocytosis without evidence of infections,
so repeat it with review of literatures.
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KEYWORD
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